iHILIC®
iHILIC columns are designed for the separation and purification of polar and hydrophilic compounds using Hydrophilic Interaction Liquid Chromatography (HILIC). The packed stationary phases are zwitterionic charge modulated amide silica or polymer particles which are covalently bonded with neutral, positively charged, and negatively charged hydrophilic functional groups. Therefore, the separation mechanism with iHILIC columns is based on a combination of hydrophilic interaction, hydrogen bonding, and weak electrostatic interactions. They have unique separation selectivity and high separation efficiency. iHILIC columns are available in four different surface chemistries, providing complementary selectivity.
iHILIC®-Fusion
Charge Modulated Hydroxyethyl Amide HILIC columns
UHPLC and HPLC
Silica based, 1.8, 3.5, and 5 µm
Available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
High efficiency and ultra-low column bleeding
iHILIC®-Fusion(+)
Charge Modulated Hydroxyethyl Amide HILIC Columns
HPLC and UHPLC, with enhanced retention for anions
Silica based, 1.8, 3.5, and 5 µm
Available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
High efficiency and ultra-low bleeding
iHILIC®-Fusion(P)
Charge Modulated Amide HILIC columns
Polymer based, 5 µm
Available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
Stable at basic pH with range pH 1-10
Ultra-low bleeding
iHILIC®-(P) Classic
Charge Modulated Diol HILIC columns
Polymer based, 5 µm
Available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
Stable at basic pH with range pH 1-10
Ultra-low bleeding
